Identification of SNP interactions using logic regression

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Identification of SNP interactions using logic regression.

Interactions of single nucleotide polymorphisms (SNPs) are assumed to be responsible for complex diseases such as sporadic breast cancer. Important goals of studies concerned with such genetic data are thus to identify combinations of SNPs that lead to a higher risk of developing a disease and to measure the importance of these interactions. There are many approaches based on classification met...

متن کامل

Identification of Genetic Polymorphism Interactions in Sporadic Alzheimer’s Disease Using Logic Regression

Objectives: Genetic polymorphism interactions are among the important factors in affliction with complex diseases like Alzheimer’s disease. The important goal of genetic association studies is to identify a combination of polymorphisms and measure their importance in increasing the risk of occurrence of such diseases. In this study, feature selection approach of logic regression was used to ide...

متن کامل

identification of genetic polymorphism interactions in sporadic alzheimer’s disease using logic regression

objectives: genetic polymorphism interactions are among the important factors in affliction with complex diseases like alzheimer’s disease. the important goal of genetic association studies is to identify a combination of polymorphisms and measure their importance in increasing the risk of occurrence of such diseases. in this study, feature selection approach of logic regression was used to ide...

متن کامل

SNP-SNP Interactions Discovered by Logic Regression Explain Crohn's Disease Genetics

In genome-wide association studies (GWAS), the association between each single nucleotide polymorphism (SNP) and a phenotype is assessed statistically. To further explore genetic associations in GWAS, we considered two specific forms of biologically plausible SNP-SNP interactions, 'SNP intersection' and 'SNP union,' and analyzed the Crohn's Disease (CD) GWAS data of the Wellcome Trust Case Cont...

متن کامل

Extension of Logic regression to Longitudinal data: Transition Logic Regression

Logic regression is a generalized regression and classification method that is able to make Boolean combinations as new predictive variables from the original binary variables. Logic regression was introduced for case control or cohort study with independent observations. Although in various studies, correlated observations occur due to different reasons, logic regression have not been studi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biostatistics

سال: 2007

ISSN: 1465-4644,1468-4357

DOI: 10.1093/biostatistics/kxm024